Sr. Research Scientist I - Biomarker

  • Full time
  • United States - California - Foster City

Hiring company: Gilead

:

The Biomarker Sciences department is seeking an experienced scientist who will work in a multidisciplinary team environment to generate and interpret data from translational and clinical studies.  The Senior Research Scientist I will be responsible for the development and execution of biomarker strategies for programs in the field of fibrosis and/or inflammation.  Experience in the analysis of multi-dimensional data sets and a strong understanding of mechanisms and pathways underlying fibrotic and/or inflammatory diseases is highly desirable.

Responsibilities:

  • This position will report to the Director of Biomarker Science in the Fibrosis/Inflammation group
  • Lead cross-functional biomarker teams in the execution of clinical biomarker and translational strategies
  • Lead the development, validation, and outsourcing of biomarker assays including pharmacodynamic, predictive, prognostic, safety, and other biomarkers
  • Collaborate with Research Biology, Clinical Research, and Clinical Data Sciences to generate, analyze, and interpret data from clinical trials and human translational studies
  • Strong experimental background in hypothesis-driven biological/translational research with demonstrated ability to execute well-designed experiments
  • Experience with genomic, epigenetic, gene expression, metabolomic, multiplexed protein detection or other related emerging platforms or data sets is desirable
  • Must be able to work independently and effectively on multiple programs in a fast-paced matrixed environment
  • Excellent collaboration, communication, and interpersonal skills are required
  • Must be motivated, team and detail-orientated, and results focused

Technical Skills:

  • Demonstrated expertise in fibrosis, inflammation, or related field
  • Analysis and interpretation of preclinical and clinical biomarker data
  • Ability to integrate complex scientific ideas, generate and execute testable hypotheses
  • Broad understanding of drug discovery and development in both early and late stage development and familiarity with regulatory approval process
  • Knowledge of biomarker discovery and development, including assay development and validation, clinical discovery of biomarkers, and mechanism-of-action/translational studies
  • Authoring of biomarker strategy documents and biomarker specific portions of clinical protocols
  • Strong verbal and written communication skills
  • Proven publication record
  • Basic understanding of intellectual property, contracting terms, and provisions

Experience:

  • PhD and a minimum of 4+ years of directly relevant post graduate academic and/or industry experience in fibrosis, inflammation, biomarkers, or other related medical science field.   Position title will be dependent on related experience.
  • Candidate must be detail-orientated with excellent record keeping and organizational skills
  • Must be a highly flexible, results-oriented, and independent self-starter who enjoys working in a fast-paced and dynamic multidisciplinary environment.


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